6FMF
Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neuropilin-1 | polymer | 158 | 17917.3 | 1 | UniProt (O14786) Pfam (PF00754) | Homo sapiens (Human) | Vascular endothelial cell growth factor 165 receptor |
| 2 | B (A) | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid | non-polymer | 584.7 | 1 | Chemie (DUE) | |||
| 3 | C (A) | trifluoroacetic acid | non-polymer | 114.0 | 1 | Chemie (TFA) | |||
| 4 | D (A) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 273 - 427 (UniProt: O14786)
| PDB | External Database | Details |
|---|---|---|
| Gly 270 | - | expression tag |
| His 271 | - | expression tag |
| Met 272 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17917.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 698.7 | |
| All* | Total formula weight | 18616.0 |
