6FL5
Structure of human SHMT1-H135N-R137A-E168N mutant at 3.6 Ang. resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D, G, J | Serine hydroxymethyltransferase, cytosolic | polymer | 471 | 51695.8 | 4 | UniProt (P34896) Pfam (PF00464) In PDB | Homo sapiens (Human) | SHMT,Glycine hydroxymethyltransferase,Serine methylase |
2 | A, D, G, J | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 4 | Chemie (PLP) | |||
3 | A, G, J | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) |
Sequence modifications
A, D, G, J: 11 - 481 (UniProt: P34896)
PDB | External Database | Details |
---|---|---|
Asn 135 | His 135 | engineered mutation |
Ala 137 | Arg 137 | engineered mutation |
Asn 168 | Glu 168 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 206783.2 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1130.4 | |
All* | Total formula weight | 207913.6 |