6FKZ
Crystal structure of zebrafish Sirtuin 5 in complex with 3-(phenylthio)succinyl-CPS1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | NAD-dependent protein deacylase sirtuin-5, mitochondrial | polymer | 284 | 31495.0 | 2 | UniProt (Q6DHI5) Pfam (PF02146) In PDB | Danio rerio (Zebrafish) | Regulatory protein SIR2 homolog 5 |
| 2 | E | 3(S)-(phenylthio)succinyl-CPS1 peptide | polymer | 8 | 1210.4 | 1 | Homo sapiens | ||
| 3 | H | 3(R)-(phenylthio)succinyl-CPS1 peptide | polymer | 8 | 1176.3 | 1 | Homo sapiens | ||
| 4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | B | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 7 | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 305 (UniProt: Q6DHI5)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Ile 23 | - | expression tag |
| Asp 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Phe 26 | - | expression tag |
| Thr 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65376.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 461.2 | |
| All* | Total formula weight | 65838.0 |
