6FJC
Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 3,4,5-trisphosphate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Protein KIBRA | polymer | 140 | 15866.0 | 2 | UniProt (Q8IX03) Pfam (PF00168) In PDB | Homo sapiens (Human) | HBeAg-binding protein 3,Kidney and brain protein,KIBRA,WW domain-containing protein 1 |
2 | A, B | GLYCEROL | non-polymer | 92.1 | 15 | Chemie (GOL) | |||
3 | A | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE | non-polymer | 716.4 | 1 | Chemie (4PT) | |||
4 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
5 | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B: 658 - 785 (UniProt: Q8IX03)
PDB | External Database | Details |
---|---|---|
Met 646 | - | initiating methionine |
Arg 647 | - | expression tag |
Gly 648 | - | expression tag |
Ser 649 | - | expression tag |
His 650 | - | expression tag |
His 651 | - | expression tag |
His 652 | - | expression tag |
His 653 | - | expression tag |
His 654 | - | expression tag |
His 655 | - | expression tag |
Gly 656 | - | expression tag |
Ser 657 | - | expression tag |
Ala 771 | Cys 771 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31732.1 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 2193.8 | |
All* | Total formula weight | 33925.9 |