6FD6
Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 30 days post crystallization (with AMP and PPi products fully generated)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Adenine phosphoribosyltransferase | polymer | 178 | 19411.5 | 2 | UniProt (P07741) Pfam (PF00156) | Homo sapiens (Human) | APRT |
| 2 | C, E (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 3 | D, G (A, B) | PYROPHOSPHATE | non-polymer | 178.0 | 2 | Chemie (PPV) | |||
| 4 | F (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 180 (UniProt: P07741)
| PDB | External Database | Details |
|---|---|---|
| Phe 105 | Tyr 105 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38822.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1074.7 | |
| All* | Total formula weight | 39897.6 |
