6F4T

Human JMJD5 (W414C) in complex with Mn(II), NOG and RCCD1 (139-143) (complex-5)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	JmjC domain-containing protein 5	polymer	255	29471.2	1	UniProt (Q8N371) Pfam (PF13621)	Homo sapiens (Human)	Jumonji domain-containing protein 5,Lysine-specific demethylase 8
2	B (B)	RCC1 domain-containing protein 1	polymer	5	583.7	1	UniProt (A6NED2)	Homo sapiens
3	C (A)	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
4	D (A)	N-OXALYLGLYCINE	non-polymer		147.1	1	Chemie (OGA)
5	E, F, G (A)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
6	H (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
7	I, J (A, B)	water	water		18.0	338	Chemie (HOH)

Sequence modifications

A: 183 - 416 (UniProt: Q8N371)

PDB	External Database	Details
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
Ser 168	-	expression tag
Ser 169	-	expression tag
Gly 170	-	expression tag
Val 171	-	expression tag
Asp 172	-	expression tag
Leu 173	-	expression tag
Gly 174	-	expression tag
Thr 175	-	expression tag
Glu 176	-	expression tag
Asn 177	-	expression tag
Leu 178	-	expression tag
Tyr 179	-	expression tag
Phe 180	-	expression tag
Gln 181	-	expression tag
Ser 182	-	expression tag
Ala 217	Cys 217	engineered mutation
Ala 232	Cys 232	engineered mutation
Cso 414	Trp 414	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30054.8
Non-Polymers*	Number of molecules	6
	Total formula weight	600.4
All*	Total formula weight	30655.3

*Water molecules are not included.