6F4T
Human JMJD5 (W414C) in complex with Mn(II), NOG and RCCD1 (139-143) (complex-5)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 501 |
| Chain | Residue |
| A | HIS321 |
| A | ASP323 |
| A | HIS400 |
| A | OGA502 |
| B | HOH201 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue OGA A 502 |
| Chain | Residue |
| A | ASP323 |
| A | ASN327 |
| A | LEU329 |
| A | LYS336 |
| A | HIS400 |
| A | VAL402 |
| A | SER412 |
| A | MN501 |
| A | HOH728 |
| B | CYS139 |
| A | TYR272 |
| A | TRP310 |
| A | SER318 |
| A | HIS321 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ARG189 |
| A | GLU266 |
| A | ASP293 |
| A | TYR294 |
| A | HOH630 |
| A | HOH708 |
| A | HOH755 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | GLN250 |
| A | LEU252 |
| A | ARG335 |
| A | HOH605 |
| A | HOH632 |
| A | HOH772 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | GLU257 |
| A | SER260 |
| A | HOH609 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue TRS A 506 |
| Chain | Residue |
| A | LEU200 |
| A | VAL201 |
| A | GLY203 |
| A | GLN326 |
| A | TYR350 |
| A | LYS372 |
| A | PHE373 |
| A | VAL396 |
| A | HOH603 |
| A | HOH612 |
| A | HOH633 |
| A | HOH669 |
| A | HOH689 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: (3R)-3-hydroxyarginine => ECO:0000269|PubMed:29563586 |
| Chain | Residue | Details |
| B | ARG141 | |
| A | GLN275 | |
| A | SER318 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22851697, ECO:0000269|PubMed:29459673, ECO:0000269|PubMed:29563586, ECO:0000305|PubMed:24100311, ECO:0007744|PDB:3UYJ, ECO:0007744|PDB:4GJZ, ECO:0007744|PDB:4QU1, ECO:0007744|PDB:5FBJ |
| Chain | Residue | Details |
| A | TYR272 | |
| A | ASN327 | |
| A | LYS336 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000305|PubMed:22851697, ECO:0000305|PubMed:24100311, ECO:0007744|PDB:4GJY, ECO:0007744|PDB:4GJZ |
| Chain | Residue | Details |
| A | HIS321 | |
| A | ASP323 | |
| A | HIS400 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22851697, ECO:0000269|PubMed:29459673, ECO:0000269|PubMed:29563586, ECO:0007744|PDB:3UYJ, ECO:0007744|PDB:4GJZ |
| Chain | Residue | Details |
| A | CSO414 |
