6F29
Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with (S)-1-[2-Amino-2-carboxyethyl]-5,7-dihydrothieno[3,4-d]pyrimidin-2,4(1H,3H)-dione at resolution 2.6A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor ionotropic, kainate 3,Glutamate receptor ionotropic, kainate 3 | polymer | 258 | 29092.5 | 1 | UniProt (P42264) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluK3,Glutamate receptor 7,GluR7,GluK3,Glutamate receptor 7,GluR7 |
| 2 | B (A) | (2~{S})-2-azanyl-3-[2,4-bis(oxidanylidene)-5,7-dihydrothieno[3,4-d]pyrimidin-1-yl]propanoic acid | non-polymer | 257.3 | 1 | Chemie (CGW) | |||
| 3 | C, D (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 4 | E, F, G (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | H (A) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 4 - 118 (UniProt: P42264)
A: 121 - 258 (UniProt: P42264)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Pro 2 | - | cloning artifact |
| Gly 3 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 119 | - | linker |
| Thr 120 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29092.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 441.8 | |
| All* | Total formula weight | 29534.3 |
