6F00
Crystal Structure of human tRNA dihydrouridine synthase (20) dsRBD E423A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A, C | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | polymer | 120 | 13670.7 | 3 | UniProt (Q9NX74) Pfam (PF00035) In PDB | Homo sapiens (Human) | Dihydrouridine synthase 2,Up-regulated in lung cancer protein 8,URLC8,tRNA-dihydrouridine synthase 2-like,hDUS2 |
| 2 | B, A, C | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 3 | A, C | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
B, A, C: 338 - 450 (UniProt: Q9NX74)
| PDB | External Database | Details |
|---|---|---|
| Met 337 | - | initiating methionine |
| Ala 423 | Glu 423 | engineered mutation |
| His 451 | - | expression tag |
| His 452 | - | expression tag |
| His 453 | - | expression tag |
| His 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41012.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1421.1 | |
| All* | Total formula weight | 42433.1 |
