6EY7
Human cytomegalovirus terminase nuclease domain, Mn soaked, inhibitor bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | UL89 HCMV terminase | polymer | 279 | 31817.9 | 4 | UniProt (P16732) Pfam (PF02499) In PDB | Human herpesvirus 5 strain AD169 | |
| 2 | A, B, C, D | MANGANESE (II) ION | non-polymer | 54.9 | 10 | Chemie (MN) | |||
| 3 | A, B, C, D | 4-[(4-fluorophenyl)methyl-methyl-amino]-2,4-bis(oxidanylidene)butanoic acid | non-polymer | 253.2 | 4 | Chemie (C3W) | |||
| 4 | D | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 400 - 674 (UniProt: P16732)
| PDB | External Database | Details |
|---|---|---|
| Met 396 | - | initiating methionine |
| Gly 397 | - | expression tag |
| His 398 | - | expression tag |
| His 399 | - | expression tag |
| His 400 | Val 400 | conflict |
| His 401 | Arg 401 | conflict |
| His 402 | Lys 402 | conflict |
| His 403 | Thr 403 | conflict |
| Asp 404 | Ala 404 | conflict |
| Tyr 405 | Asn 405 | conflict |
| Asp 406 | Met 406 | conflict |
| Ile 407 | Phe 407 | conflict |
| Pro 408 | Met 408 | conflict |
| Thr 409 | Pro 409 | conflict |
| Thr 410 | Gly 410 | conflict |
| Glu 411 | Ala 411 | conflict |
| Asn 412 | Phe 412 | conflict |
| Leu 413 | Met 413 | conflict |
| Tyr 414 | Asp 414 | conflict |
| Phe 415 | Glu 415 | conflict |
| Gln 416 | Ile 416 | conflict |
| Gly 417 | Ile 417 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127271.6 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1597.7 | |
| All* | Total formula weight | 128869.3 |
