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6EXM

The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK202)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BListeriolysin positive regulatory factor Apolymer23927457.52UniProt (Q4TVQ0)
UniProt (by SIFTS) (P22262)
In PDB
Listeria monocytogenesListeriolysin positive regulatory protein,Listeriolysin regulatory protein,Pleitrophic regulatory factor A,Positive regulatory factor A,PrfA,Transcriptional regulator
2A, B[(3~{R})-3-carboxy-7-[(2,3-dimethylphenyl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azaniumnon-polymer359.52Chemie (QQH)
3A, BSODIUM IONnon-polymer23.03Chemie (NA)
4AISOPROPYL ALCOHOLnon-polymer60.14Chemie (IPA)
5waterwater18.0326Chemie (HOH)
Sequence modifications
A, B: 1 - 237 (UniProt: Q4TVQ0)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight54915.0
Non-Polymers*Number of molecules9
Total formula weight1028.3
All*Total formula weight55943.3
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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