6EUV

Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, C, F, I)	Polymerase basic protein 2	polymer	290	32524.3	4	UniProt (P31345) Pfam (PF20950) Pfam (PF00604)	Influenza A virus (strain A/Victoria/3/1975 H3N2)	RNA-directed RNA polymerase subunit P3
2	E, F, H, I, K... (A, C, F, I)	(2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid	non-polymer		399.4	6	Chemie (21G)
3	G, J, L, N (A, C, F, I)	NICKEL (II) ION	non-polymer		58.7	4	Chemie (NI)
4	O, P, Q, R (A, C, F, I)	water	water		18.0	102	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	130097.3
Non-Polymers*	Number of molecules	10
	Total formula weight	2631.1
All*	Total formula weight	132728.4

*Water molecules are not included.