6EUV
Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, F, I | Polymerase basic protein 2 | polymer | 290 | 32524.3 | 4 | UniProt (P31345) Pfam (PF20950) Pfam (PF00604) In PDB | Influenza A virus (strain A/Victoria/3/1975 H3N2) | RNA-directed RNA polymerase subunit P3 |
2 | A, C, F, I | (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid | non-polymer | 399.4 | 6 | Chemie (21G) | |||
3 | A, C, F, I | NICKEL (II) ION | non-polymer | 58.7 | 4 | Chemie (NI) | |||
4 | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 130097.3 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 2631.1 | |
All* | Total formula weight | 132728.4 |