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6EUV

Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, F, IPolymerase basic protein 2polymer29032524.34UniProt (P31345)
Pfam (PF20950)
Pfam (PF00604)
In PDB
Influenza A virus (strain A/Victoria/3/1975 H3N2)RNA-directed RNA polymerase subunit P3
2A, C, F, I(2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acidnon-polymer399.46Chemie (21G)
3A, C, F, INICKEL (II) IONnon-polymer58.74Chemie (NI)
4waterwater18.0102Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight130097.3
Non-Polymers*Number of molecules10
Total formula weight2631.1
All*Total formula weight132728.4
*Water molecules are not included.

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PDB entries from 2024-07-24

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