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6ET9

Structure of the acetoacetyl-CoA-thiolase/HMG-CoA-synthase complex from Methanothermococcus thermolithotrophicus at 2.75 A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Acetyl-CoA acetyltransferase thiolasepolymer39241943.44Pfam (PF00108)
Pfam (PF22691)
UniProt (by SIFTS) (A0A384E138)
Methanothermococcus thermolithotrophicus
2E, F, G, H
(E, F, G, H)
Pfam DUF35polymer13014910.44Pfam (PF12172)
Pfam (PF01796)
UniProt (by SIFTS) (A0A384E139)
Methanothermococcus thermolithotrophicus
3I, J, K, L
(I, J, K, L)
HydroxyMethylGlutaryl-CoA synthasepolymer34937520.64Pfam (PF01154)
Pfam (PF08541)
UniProt (by SIFTS) (A0A384E143)
Methanothermococcus thermolithotrophicus
4M, TA, Z
(A, J, D)
SODIUM IONnon-polymer23.03Chemie (NA)
5AA, HA, JA, MA, N...
(D, F, G, H, A...)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.111Chemie (TRS)
6BA, OA, PA, Q, T...
(D, I, A, B, J...)
POTASSIUM IONnon-polymer39.18Chemie (K)
7EA, FA, KA, NA, QA...
(E, G, H, I, C)
CHLORIDE IONnon-polymer35.56Chemie (CL)
8Y
(D)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
9CA, RA, SA, VA, XA...
(D, I, J, K, L)
GLYCEROLnon-polymer92.16Chemie (GOL)
10DA, GA, IA, LA
(E, F, G, H)
ZINC IONnon-polymer65.44Chemie (ZN)
11AB, BB, CB, DB, EB...
(B, C, D, E, F...)
waterwater18.0468Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight377497.4
Non-Polymers*Number of molecules39
Total formula weight2776.6
All*Total formula weight380274.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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