6ERH
Complex of XLF and heterodimer Ku bound to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | X-ray repair cross-complementing protein 6 | polymer | 544 | 62629.6 | 2 | UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) | Homo sapiens (Human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 2 | B, D (B, D) | X-ray repair cross-complementing protein 5 | polymer | 572 | 65356.8 | 2 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) | Homo sapiens (Human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 3 | E, H (F, O) | DNA (34-MER) | polymer | 34 | 10325.7 | 2 | synthetic construct | ||
| 4 | F, I (K, R) | DNA (21-MER) | polymer | 21 | 6506.2 | 2 | synthetic construct | ||
| 5 | G, J (M, T) | Non-homologous end-joining factor 1 | polymer | 19 | 2273.8 | 2 | UniProt (Q9H9Q4) | Homo sapiens | Protein cernunnos,XRCC4-like factor |
| 6 | K, L (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | M, N, O, P, Q... (A, B, C, D, F...) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
B, D: 2 - 555 (UniProt: P13010)
| PDB | External Database | Details |
|---|---|---|
| Met -16 | - | initiating methionine |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| Glu -5 | - | expression tag |
| Asn -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Tyr -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Gln 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 294184.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 294376.4 |
