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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6EPD

Substrate processing state 26S proteasome (SPS1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProteasome subunit alpha type-6polymer24627432.51UniProt (P60901)
Pfam (PF00227)
Pfam (PF10584)
In PDB		Rattus norvegicus (Rat)Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain
2BProteasome subunit alpha type-2polymer23425955.51UniProt (P17220)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3
3CProteasome subunit alpha type-4polymer26129539.81UniProt (P21670)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L
4DProteasome subunit alpha type-7polymer25428369.41UniProt (P48004)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Proteasome subunit RC6-1
5EProteasome subunit alpha type-5polymer24126416.81UniProt (P34064)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome zeta chain
6FProteasome subunit alpha type-1polymer26329557.51UniProt (P18420)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain subunit C2,Multicatalytic endopeptidase complex subunit C2,Proteasome component C2,Proteasome nu chain
7GProteasome subunit alpha type-3polymer25528456.31UniProt (P18422)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8,Proteasome subunit K
81Proteasome subunit beta type-6polymer23825309.61UniProt (P28073)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain delta chain,Multicatalytic endopeptidase complex delta chain,Proteasome chain 5,Proteasome delta chain,Proteasome subunit Y
92Proteasome subunit beta type-7polymer27729963.51UniProt (Q9JHW0)
Pfam (PF00227)
Pfam (PF12465)
In PDB		Rattus norvegicus (Rat)Macropain chain Z,Multicatalytic endopeptidase complex chain Z,Proteasome subunit Z
103Proteasome subunit beta type-3polymer20522988.91UniProt (P40112)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Proteasome chain 13,Proteasome component C10-II,Proteasome theta chain
114Proteasome subunit beta type-2polymer20122941.41UniProt (P40307)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain subunit C7-I,Multicatalytic endopeptidase complex subunit C7-I,Proteasome component C7-I
125Proteasome subunit beta type-5polymer26328615.41UniProt (P28075)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain epsilon chain,Multicatalytic endopeptidase complex epsilon chain,Proteasome chain 6,Proteasome epsilon chain,Proteasome subunit X
136Proteasome subunit beta type-1polymer24026511.31UniProt (P18421)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain subunit C5,Multicatalytic endopeptidase complex subunit C5,Proteasome component C5,Proteasome gamma chain
147Proteasome subunit beta type-4polymer26329226.21UniProt (P34067)
Pfam (PF00227)
In PDB		Rattus norvegicus (Rat)Macropain beta chain,Multicatalytic endopeptidase complex beta chain,Proteasome beta chain,Proteasome chain 3,RN3
15W26S proteasome subunit S5apolymer37740775.61UniProt (Q9ESH1)
Pfam (PF13519)
Pfam (PF02809)
In PDB		Rattus norvegicus (Rat)Psmd4 protein
16VProteasome (Prosome, macropain) 26S subunit, non-ATPase, 14polymer31034620.01UniProt (Q4V8E2)
Pfam (PF01398)
In PDB		Rattus norvegicus (Rat)Proteasome 26S subunit,non-ATPase 14,Psmd14 protein,RCG26455,isoform CRA_b
17TProteasome 26S subunit, non-ATPase 8polymer35339932.11UniProt (F1LMQ3)
Pfam (PF10075)
In PDB		Rattus norvegicus (Rat)
18YRCG28037polymer708284.61UniProt (D3ZHW9)
Pfam (PF05160)
In PDB		Rattus norvegicus (Rat)SEM1,26S proteasome complex subunit
19Z26S proteasome non-ATPase regulatory subunit 2polymer908100300.51UniProt (Q4FZT9)
Pfam (PF17781)
Pfam (PF01851)
Pfam (PF18051)
In PDB		Rattus norvegicus (Rat)
20N26S proteasome non-ATPase regulatory subunit 1polymer953105870.11UniProt (O88761)
Pfam (PF21505)
Pfam (PF01851)
Pfam (PF13646)
Pfam (PF18004)
In PDB		Rattus norvegicus (Rat)26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112
21SProteasome (Prosome, macropain) 26S subunit, non-ATPase, 3polymer53060778.21UniProt (Q5U2S7)
UniProt (by SIFTS) (A6HIT6)
In PDB		Rattus norvegicus (Rat)Proteasome (Prosome,macropain) 26S subunit,non-ATPase,3,isoform CRA_b,Proteasome 26S subunit,non-ATPase 3
22PProteasome (Prosome, macropain) 26S subunit, non-ATPase, 12polymer45653011.21UniProt (Q5XIC6)
Pfam (PF01399)
Pfam (PF18098)
In PDB		Rattus norvegicus (Rat)Proteasome 26S subunit,non-ATPase 12
23Q26S proteasome non-ATPase regulatory subunit 11polymer42247526.71UniProt (F1LMZ8)
Pfam (PF18055)
Pfam (PF01399)
Pfam (PF18503)
In PDB		Rattus norvegicus (Rat)26S proteasome regulatory subunit RPN6
24RProteasome (Prosome, macropain) 26S subunit, non-ATPase, 6polymer38945658.41UniProt (Q6PCT9)
Pfam (PF10602)
Pfam (PF01399)
Pfam (PF21154)
In PDB		Rattus norvegicus (Rat)Proteasome (Prosome,macropain) 26S subunit,non-ATPase,6,isoform CRA_a,Proteasome 26S subunit,non-ATPase 6
25UProteasome (Prosome, macropain) 26S subunit, non-ATPase, 7 (Predicted)polymer32036551.81UniProt (D4AEH3)
Pfam (PF01398)
Pfam (PF13012)
In PDB		Rattus norvegicus (Rat)Proteasome 26S subunit,non-ATPase 7
26O26S proteasome non-ATPase regulatory subunit 13polymer37642867.21UniProt (B0BN93)
Pfam (PF01399)
In PDB		Rattus norvegicus (Rat)26S proteasome regulatory subunit RPN9,26S proteasome regulatory subunit S11,26S proteasome regulatory subunit p40.5
27H26S proteasome regulatory subunit 7polymer43348640.71UniProt (Q63347)
Pfam (PF21236)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Rattus norvegicus (Rat)26S proteasome AAA-ATPase subunit RPT1,Proteasome 26S subunit ATPase 2,Protein MSS1
28I26S proteasome regulatory subunit 4polymer44049260.51UniProt (P62193)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Rattus norvegicus (Rat)P26s4,26S proteasome AAA-ATPase subunit RPT2,Proteasome 26S subunit ATPase 1
29K26S proteasome regulatory subunit 6Bpolymer41847468.21UniProt (Q63570)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Rattus norvegicus (Rat)26S proteasome AAA-ATPase subunit RPT3,Proteasome 26S subunit ATPase 4,S6 ATPase,Tat-binding protein 7,TBP-7
30LProteasome 26S subunit, ATPase 6polymer40345867.01UniProt (G3V6W6)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Rattus norvegicus (Rat)RCG61291
31M26S proteasome regulatory subunit 6Apolymer44249611.81UniProt (Q6P6U2)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
UniProt (by SIFTS) (Q63569)
In PDB		Rattus norvegicus (Rat)Proteasome (Prosome,macropain) 26S subunit,ATPase 3,isoform CRA_a
32J26S proteasome regulatory subunit 8polymer40645694.01UniProt (P62198)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Rattus norvegicus (Rat)26S proteasome AAA-ATPase subunit RPT6,Proteasome 26S subunit ATPase 5,Proteasome subunit p45,Thyroid hormone receptor-interacting protein 1,TRIP1,p45/SUG
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains32
Total formula weight1284003.1
All*Total formula weight1284003.1
*Water molecules are not included.

218500

PDB entries from 2024-04-17

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