6EP8
InhA Y158F mutant in complex with NADH from Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 272 | 28821.1 | 1 | UniProt (P9WGR1) Pfam (PF13561) | Mycobacterium tuberculosis H37Rv | Enoyl-ACP reductase,FAS-II enoyl-ACP reductase,NADH-dependent 2-trans-enoyl-ACP reductase |
| 2 | B, D, E, F (A) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 3 | C (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 4 | G, H, I, J, K... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | M (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 6 | N (A) | water | water | 18.0 | 264 | Chemie (HOH) |
Sequence modifications
A: 1 - 269 (UniProt: P9WGR1)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Phe 158 | Tyr 158 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28821.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1426.1 | |
| All* | Total formula weight | 30247.2 |
