6ELW
High resolution structure of selenocysteine containing human GPX4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | polymer | 192 | 21806.6 | 1 | UniProt (P36969) Pfam (PF00255) In PDB | Homo sapiens (Human) | PHGPx,Glutathione peroxidase 4,GSHPx-4 |
2 | A | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
3 | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A: 2 - 170 (UniProt: P36969)
PDB | External Database | Details |
---|---|---|
Met -21 | - | initiating methionine |
Gly -20 | - | expression tag |
Ser -19 | - | expression tag |
Ser -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
Ser -11 | - | expression tag |
Ser -10 | - | expression tag |
Gly -9 | - | expression tag |
Leu -8 | - | expression tag |
Val -7 | - | expression tag |
Pro -6 | - | expression tag |
Arg -5 | - | expression tag |
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
His -2 | - | expression tag |
Met -1 | - | expression tag |
Leu 0 | - | expression tag |
Glu 1 | - | expression tag |
Ala 2 | Cys 2 | engineered mutation |
Ala 10 | Cys 10 | engineered mutation |
Ser 37 | Cys 37 | engineered mutation |
Ala 66 | Cys 66 | engineered mutation |
Ser 75 | Cys 75 | engineered mutation |
Ala 107 | Cys 107 | engineered mutation |
Ala 148 | Cys 148 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 21806.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 106.4 | |
All* | Total formula weight | 21913.0 |