6EKK
Crystal structure of GEF domain of DENND 1A in complex with Rab GTPase Rab35-GDP bound state.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DENN domain-containing protein 1A | polymer | 393 | 45006.2 | 2 | UniProt (Q8TEH3) Pfam (PF03456) Pfam (PF02141) Pfam (PF03455) | Homo sapiens (Human) | Connecdenn 1,Connecdenn,Protein FAM31A |
| 2 | C, D (C, D) | Ras-related protein Rab-35 | polymer | 176 | 20077.7 | 2 | UniProt (Q15286) Pfam (PF00071) | Homo sapiens (Human) | GTP-binding protein RAY,Ras-related protein Rab-1C |
| 3 | E, F, J, K, L... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 4 | G, H, I, M, N... (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | T, W (C, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 6 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 860 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130167.8 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2247.5 | |
| All* | Total formula weight | 132415.3 |
