6EKK
Crystal structure of GEF domain of DENND 1A in complex with Rab GTPase Rab35-GDP bound state.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DENN domain-containing protein 1A | polymer | 393 | 45006.2 | 2 | UniProt (Q8TEH3) Pfam (PF03456) Pfam (PF02141) Pfam (PF03455) | Homo sapiens (Human) | Connecdenn 1,Connecdenn,Protein FAM31A |
| 2 | C, D (C, D) | Ras-related protein Rab-35 | polymer | 176 | 20077.7 | 2 | UniProt (Q15286) Pfam (PF00071) | Homo sapiens (Human) | GTP-binding protein RAY,Ras-related protein Rab-1C |
| 3 | E, F, J, K, L... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 4 | G, H, I, M, N... (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | T, W (C, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 6 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 860 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130167.8 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2247.5 | |
| All* | Total formula weight | 132415.3 |
