6EHT
Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proliferating cell nuclear antigen | polymer | 254 | 28036.0 | 2 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens (Human) | PCNA,Cyclin |
| 2 | C (C) | Proliferating cell nuclear antigen | polymer | 256 | 28287.3 | 1 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens (Human) | PCNA,Cyclin |
| 3 | D, E (D, E) | PCNA-associated factor | polymer | 20 | 2362.8 | 2 | UniProt (Q15004) | Homo sapiens | Hepatitis C virus NS5A-transactivated protein 9,HCV NS5A-transactivated protein 9,Overexpressed in anaplastic thyroid carcinoma 1,OEATC-1,PCNA-associated factor of 15 kDa,p15PAF,PCNA-clamp-associated factor |
| 4 | F (F) | DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3') | polymer | 10 | 3109.1 | 1 | Homo sapiens | ||
| 5 | G (G) | DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3') | polymer | 10 | 2980.0 | 1 | Homo sapiens | ||
| 6 | H, I, J (A, B, C) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
C: 1 - 255 (UniProt: P12004)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 95174.1 | |
| All* | Total formula weight | 95174.1 |
