6EHO
Dimer of the Sortilin Vps10p domain at low pH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sortilin | polymer | 723 | 80380.8 | 1 | UniProt (Q99523) Pfam (PF15902) Pfam (PF15901) | Homo sapiens (Human) | 100 kDa NT receptor,Glycoprotein 95,Gp95,Neurotensin receptor 3,NTR3 |
| 2 | B (B) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 3 | C (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
A: 1 - 723 (UniProt: Q99523)
| PDB | External Database | Details |
|---|---|---|
| Gly 43 | Arg 76 | engineered mutation |
| Gly 44 | Arg 77 | engineered mutation |
| Met 617 | Val 650 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 80380.8 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1921.8 | |
| All* | Total formula weight | 82302.6 |
