6EG2
Crystal structure of human BRM in complex with compound 16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2 | polymer | 621 | 69653.1 | 1 | UniProt (P0AEY0) UniProt (P51531) Pfam (PF01547) Pfam (PF00176) UniProt (by SIFTS) (P0AEX9) | Escherichia coli O157:H7 | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,ATP-dependent helicase SMARCA2,BRG1-associated factor 190B,BAF190B,Protein brahma homolog,hBRM,SNF2-alpha,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 |
| 2 | B (A) | N-(5-amino-2-chloropyridin-4-yl)-N'-(4-bromo-3-{[3-(hydroxymethyl)phenyl]ethynyl}-1,2-thiazol-5-yl)urea | non-polymer | 478.8 | 1 | Chemie (J7J) | |||
| 3 | C, D (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
| 4 | E (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 335 - 700 (UniProt: P0AEY0)
A: 705 - 955 (UniProt: P51531)
| PDB | External Database | Details |
|---|---|---|
| Ala 416 | Asp 108 | conflict |
| Ala 417 | Lys 109 | conflict |
| Ala 506 | Glu 198 | conflict |
| Ala 507 | Asn 199 | conflict |
| Ala 573 | Lys 265 | conflict |
| Asn 701 | - | linker |
| Ala 702 | - | linker |
| Ala 703 | - | linker |
| Ala 704 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 69653.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 598.9 | |
| All* | Total formula weight | 70252.0 |
