6E6J
BRD2_Bromodomain2 complex with inhibitor 744
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Bromodomain-containing protein 2 | polymer | 112 | 13184.1 | 6 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | A, B, C, D, E... | N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl]-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | non-polymer | 491.6 | 6 | Chemie (HWV) | |||
| 3 | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 348 - 455 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Gly 344 | - | expression tag |
| Ser 345 | - | expression tag |
| His 346 | - | expression tag |
| Met 347 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 79104.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2949.3 | |
| All* | Total formula weight | 82054.2 |
