6E68

NAMPT co-crystal with inhibitor compound 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nicotinamide phosphoribosyltransferase	polymer	480	54491.7	2	UniProt (P43490) Pfam (PF18127) Pfam (PF04095)	Homo sapiens (Human)	Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin
2	C, E (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
3	D, F (A, B)	(2E)-N-{4-[1-(3-aminobenzene-1-carbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide	non-polymer		406.5	2	Chemie (HVM)
4	G, H (A, B)	water	water		18.0	1153	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	108983.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1003.0
All*	Total formula weight	109986.5

*Water molecules are not included.