6E68
NAMPT co-crystal with inhibitor compound 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nicotinamide phosphoribosyltransferase | polymer | 480 | 54491.7 | 2 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) In PDB | Homo sapiens (Human) | Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin |
2 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
3 | A, B | (2E)-N-{4-[1-(3-aminobenzene-1-carbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide | non-polymer | 406.5 | 2 | Chemie (HVM) | |||
4 | water | water | 18.0 | 1153 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 108983.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1003.0 | |
All* | Total formula weight | 109986.5 |