6E53
Structure of TERT in complex with a novel telomerase inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Telomerase reverse transcriptase | polymer | 596 | 70588.7 | 1 | UniProt (Q0QHL8) Pfam (PF12009) Pfam (PF00078) Pfam (PF17984) | Tribolium castaneum (red flour beetle) | |
| 2 | B (E) | RNA/DNA hairpin | polymer | 23 | 7164.5 | 1 | Tribolium castaneum (red flour beetle) | ||
| 3 | C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E (A) | methyl 1-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-D-erythro-pentofuranosyl}-1H-indole-5-carboxylate | non-polymer | 531.2 | 1 | Chemie (HUV) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77753.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 579.8 | |
| All* | Total formula weight | 78333.0 |
