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6E4Z

Anti-PCSK9 fab 6E2 bound to the modified N-terminal peptide from PCSK9

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
6E2 heavy chainpolymer22424255.21Mus musculus (Mouse)
2B
(L)
6E2 light chainpolymer21924040.91UniProt (A0A097PUG4)
Pfam (PF07686)
Pfam (PF07654)
Mus musculus (Mouse)
3C
(P)
Proprotein convertase subtilisin/kexin type 9polymer222628.61UniProt (Q8NBP7)Homo sapiensNeural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
4D, E, F, G, H
(H, L)
ZINC IONnon-polymer65.45Chemie (ZN)
5I
(L)
SULFATE IONnon-polymer96.11Chemie (SO4)
6J, K, L
(H, L, P)
waterwater18.0122Chemie (HOH)
Sequence modifications
L: 1 - 106 (PDB: 6E4Z)
L: 107 - 214 (UniProt: A0A097PUG4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight50924.7
Non-Polymers*Number of molecules6
Total formula weight423.1
All*Total formula weight51347.8
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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