6E4Z

Anti-PCSK9 fab 6E2 bound to the modified N-terminal peptide from PCSK9

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	6E2 heavy chain	polymer	224	24255.2	1		Mus musculus (Mouse)
2	L	6E2 light chain	polymer	219	24040.9	1	UniProt (A0A097PUG4) Pfam (PF07686) Pfam (PF07654) In PDB	Mus musculus (Mouse)
3	P	Proprotein convertase subtilisin/kexin type 9	polymer	22	2628.6	1	UniProt (Q8NBP7) In PDB	Homo sapiens	Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
4	H, L	ZINC ION	non-polymer		65.4	5	Chemie (ZN)
5	L	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6		water	water		18.0	122	Chemie (HOH)

Sequence modifications

L: 1 - 106 (PDB: 6E4Z)
L: 107 - 214 (UniProt: A0A097PUG4)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	50924.7
Non-Polymers*	Number of molecules	6
	Total formula weight	423.1
All*	Total formula weight	51347.8

*Water molecules are not included.