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6E4Y

Anti-PCSK9 fab 6E2 bound to the N-terminal peptide from PCSK9, unmodified

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
6E2 heavy chainpolymer22424255.21Mus musculus (Mouse)
2B
(L)
6E2 light chainpolymer21924040.91UniProt (A0A097PUG4)
Pfam (PF07686)
Pfam (PF07654)
Mus musculus (Mouse)
3C
(P)
Proprotein convertase subtilisin/kexin type 9polymer222468.51UniProt (Q8NBP7)Homo sapiensNeural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
4D, F, G, H
(H, L, P)
ZINC IONnon-polymer65.44Chemie (ZN)
5E
(H)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6I, J, K
(H, L, P)
waterwater18.0133Chemie (HOH)
Sequence modifications
L: 1 - 106 (PDB: 6E4Y)
L: 107 - 214 (UniProt: A0A097PUG4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight50764.6
Non-Polymers*Number of molecules5
Total formula weight297.1
All*Total formula weight51061.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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