6DLG
Crystal structure of a SHIP1 surface entropy reduction mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | polymer | 463 | 52507.3 | 1 | UniProt (Q9ES52) Pfam (PF22669) | Mus musculus (Mouse) | Inositol polyphosphate-5-phosphatase of 145 kDa,SIP-145,SH2 domain-containing inositol 5'-phosphatase 1,SHIP-1,p150Ship |
| 2 | B (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 3 | C (A) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A: 402 - 861 (UniProt: Q9ES52)
| PDB | External Database | Details |
|---|---|---|
| Ser 399 | - | expression tag |
| Asn 400 | - | expression tag |
| Ala 401 | - | expression tag |
| Ala 770 | Glu 769 | engineered mutation |
| Ala 772 | Glu 771 | engineered mutation |
| Ala 773 | Glu 772 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52507.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 60.1 | |
| All* | Total formula weight | 52567.4 |
