6DJC
Crystal structure of human Bromodomain-containing protein 4 (BRD4) bromodomain with MS645
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bromodomain-containing protein 4 | polymer | 132 | 15687.1 | 2 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
2 | A | N,N'-(decane-1,10-diyl)bis{2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamide} | non-polymer | 938.0 | 1 | Chemie (CF6) | |||
3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
4 | water | water | 18.0 | 350 | Chemie (HOH) |
Sequence modifications
A, B: 44 - 173 (UniProt: O60885)
PDB | External Database | Details |
---|---|---|
Ser 42 | - | expression tag |
Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31374.2 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1434.6 | |
All* | Total formula weight | 32808.8 |