Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue CF6 A 501 |
| Chain | Residue |
| A | TRP81 |
| A | HOH678 |
| B | TRP81 |
| B | PRO82 |
| B | PHE83 |
| B | LEU92 |
| B | LEU94 |
| B | ASN140 |
| B | ASP145 |
| B | ILE146 |
| B | HOH614 |
| A | PRO82 |
| B | HOH642 |
| B | HOH711 |
| A | LEU94 |
| A | ASN140 |
| A | ASP145 |
| A | ILE146 |
| A | HOH620 |
| A | HOH633 |
| A | HOH653 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | ASP88 |
| A | HOH601 |
| A | HOH603 |
| A | HOH669 |
| A | HOH679 |
| B | TRP81 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | ILE100 |
| A | ILE101 |
| A | LYS102 |
| A | THR103 |
| A | ASN135 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ASN93 |
| A | HOH613 |
| A | HOH671 |
| A | HOH721 |
| B | LEU148 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | LYS57 |
| A | HOH686 |
| A | HOH699 |
| B | LYS99 |
| B | LYS102 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | GLU49 |
| A | SER51 |
| A | ASN52 |
| A | PRO53 |
| A | HOH604 |
| A | HOH683 |
| B | TYR137 |
| B | ILE138 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLN78 |
| A | TRP81 |
| A | HOH653 |
| B | LYS91 |
| B | LEU92 |
| B | ASN93 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | ILE100 |
| B | ILE101 |
| B | LYS102 |
| B | THR103 |
| B | ASN135 |
| B | HOH673 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| A | LYS57 |
| B | THR134 |
| B | GLU154 |
| B | HOH603 |
| B | HOH604 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFqqpvDavklnlpDYYkiIktpMdmgtIkkrlenny..Ywnaqeciqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA80-TYR139 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 212 |
| Details | Domain: {"description":"Bromo 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Acetylated histone binding","evidences":[{"source":"PubMed","id":"22464331","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
