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6DC9

Fab/epitope complex of human chimeric monoclonal antibody h4E6 targeting a phosphorylated tau epitope.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(H, I)
Fab heavy chainpolymer21923135.62Homo sapiens (Human)
2B, E
(L, M)
Fab light chainpolymer21523484.02Homo sapiens (Human)
3C, F
(P, Q)
Microtubule-associated protein taupolymer303430.62UniProt (P10636)Homo sapiensNeurofibrillary tangle protein,Paired helical filament-tau,PHF-tau
4G
(L)
GLYCEROLnon-polymer92.11Chemie (GOL)
5H, I
(L, M)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
6J, K
(H, M)
waterwater18.05Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight100100.5
Non-Polymers*Number of molecules3
Total formula weight282.0
All*Total formula weight100382.5
*Water molecules are not included.

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PDB entries from 2025-12-03

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