6D7M
Crystal structure of the W184R/W231R Importin alpha mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Peroxidase,Importin subunit alpha-1 | polymer | 510 | 55272.5 | 1 | UniProt (P52293) Pfam (PF01749) Pfam (PF00514) Pfam (PF16186) | Mus musculus (Mouse) | Importin alpha P1 |
| 2 | B, C, D (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | E (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | F (B) | SUCCINIC ACID | non-polymer | 118.1 | 1 | Chemie (SIN) | |||
| 5 | G (B) | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
B: 20 - 69 (PDB: 6D7M)
B: 70 - 529 (UniProt: P52293)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Arg 184 | Trp 184 | engineered mutation |
| Arg 231 | Trp 231 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55272.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 339.7 | |
| All* | Total formula weight | 55612.3 |
