6D7M
Crystal structure of the W184R/W231R Importin alpha mutant
Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0005515 | molecular_function | protein binding |
B | 0005634 | cellular_component | nucleus |
B | 0005654 | cellular_component | nucleoplasm |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006606 | biological_process | protein import into nucleus |
B | 0010494 | cellular_component | cytoplasmic stress granule |
B | 0014069 | cellular_component | postsynaptic density |
B | 0015031 | biological_process | protein transport |
B | 0042564 | cellular_component | NLS-dependent protein nuclear import complex |
B | 0043657 | cellular_component | host cell |
B | 0061608 | molecular_function | nuclear import signal receptor activity |
B | 0075506 | biological_process | entry of viral genome into host nucleus through nuclear pore complex via importin |
B | 0098978 | cellular_component | glutamatergic synapse |
B | 0099527 | biological_process | postsynapse to nucleus signaling pathway |
B | 0140297 | molecular_function | DNA-binding transcription factor binding |
B | 1903902 | biological_process | positive regulation of viral life cycle |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 2 |
Details | binding site for residue EDO B 601 |
Chain | Residue |
B | LEU221 |
B | ALA222 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue EDO B 602 |
Chain | Residue |
B | GLN371 |
B | VAL374 |
B | GLU411 |
B | GLN412 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue EDO B 603 |
Chain | Residue |
B | ASN361 |
B | VAL321 |
B | GLY323 |
B | THR328 |
site_id | AC4 |
Number of Residues | 1 |
Details | binding site for residue CL B 604 |
Chain | Residue |
B | GLN297 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue SIN B 605 |
Chain | Residue |
B | SER77 |
B | VAL78 |
B | ARG106 |
B | HOH734 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079 |
Chain | Residue | Details |
B | MET64 |