6D3A
Structure of human ARH3 D314E bound to ADP-ribose and magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C, D, A, B | Poly(ADP-ribose) glycohydrolase ARH3 | polymer | 366 | 39292.0 | 4 | UniProt (Q9NX46) Pfam (PF03747) In PDB | Homo sapiens (Human) | ADP-ribosylhydrolase 3,[Protein ADP-ribosylarginine] hydrolase-like protein 2 |
| 2 | C, D, A, B | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 4 | Chemie (AR6) | |||
| 3 | C, D, A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 814 | Chemie (HOH) |
Sequence modifications
C, D, A, B: 1 - 363 (UniProt: Q9NX46)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Glu 314 | Asp 314 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 157168.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2334.5 | |
| All* | Total formula weight | 159502.4 |
