6D3A
Structure of human ARH3 D314E bound to ADP-ribose and magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, D, A, B) | Poly(ADP-ribose) glycohydrolase ARH3 | polymer | 366 | 39292.0 | 4 | UniProt (Q9NX46) Pfam (PF03747) | Homo sapiens (Human) | ADP-ribosylhydrolase 3,[Protein ADP-ribosylarginine] hydrolase-like protein 2 |
| 2 | E, G, I, K (C, D, A, B) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 4 | Chemie (AR6) PubChem (192) PubChem (25113622) PubChem (25113623) PubChem (44415180) PubChem (51051599) PubChem (44144391) PubChem (445794) PubChem (447048) PubChem (89379870) PubChem (33576) PubChem (447165) PubChem (448826) PubChem (91746164) PubChem (9548001) PubChem (9547960) PubChem (122606931) PubChem (122609061) PubChem (10437766) PubChem (174159053) PubChem (140853820) PubChem (146879505) PubChem (162774256) PubChem (162782217) PubChem (163972867) PubChem (173750345) PubChem (173750346) PubChem (175675949) | |||
| 3 | F, H, J, L (C, D, A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 4 | M, N, O, P (C, D, A, B) | water | water | 18.0 | 814 | Chemie (HOH) |
Sequence modifications
C, D, A, B: 1 - 363 (UniProt: Q9NX46)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Glu 314 | Asp 314 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 157168.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2334.5 | |
| All* | Total formula weight | 159502.4 |
