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6D2P

Crystal structure of IOMA-class CLK31 Fab from an HIV-1 naive donor in complex with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.6 A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8polymer18319889.31Homo sapiens (Human)
2B
(H)
IOMAclass naive CLK31 Fab heavy chainpolymer22123697.61Homo sapiens (Human)
3C
(L)
IOMAclass naive CLK31 Fab light chainpolymer21422417.81Homo sapiens (Human)
4D, E, F, G, H
(C, H)
GLYCEROLnon-polymer92.15Chemie (GOL)
5I, J, K
(C, H, L)
waterwater18.0113Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight66004.7
Non-Polymers*Number of molecules5
Total formula weight460.5
All*Total formula weight66465.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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