6D2P

Crystal structure of IOMA-class CLK31 Fab from an HIV-1 naive donor in complex with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.6 A

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0019031	cellular_component	viral envelope

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue GOL C 201

Chain	Residue
C	HIS14
C	SER16
C	SER17
C	ASN65
C	HOH308

---

site_id	AC2
Number of Residues	2
Details	binding site for residue GOL C 202

Chain	Residue
C	ASN18
C	GLU96

---

site_id	AC3
Number of Residues	7
Details	binding site for residue GOL C 203

Chain	Residue
C	ASN146
C	ALA159
C	SER160
C	THR161
C	HOH314
C	SER137
C	VAL145

---

site_id	AC4
Number of Residues	2
Details	binding site for residue GOL H 301

Chain	Residue
H	GLU10
H	LYS19

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL H 302

Chain	Residue
C	ASP82
C	ALA84
C	LYS85
H	TYR33
H	SER99
H	GLY101
H	HOH429

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR194-HIS200
H	TYR199-HIS205

---