6D0Y

X-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	Nuclear cap-binding protein subunit 1	polymer	782	91129.4	1	UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090)	Homo sapiens (Human)	80 kDa nuclear cap-binding protein,NCBP 80 kDa subunit
2	B (A)	Nuclear cap-binding protein subunit 2	polymer	176	20047.4	1	UniProt (P52298) Pfam (PF00076)	Homo sapiens (Human)	20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1
3	C (B)	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	polymer	31	3466.6	1	UniProt (Q86YN6)	Homo sapiens	PPARGC-1-beta,PGC-1-related estrogen receptor alpha coactivator
4	D (C)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	E (A)	P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE	non-polymer		787.4	1	Chemie (GTA)
6	F, G, H (C, A, B)	water	water		18.0	274	Chemie (HOH)

Sequence modifications

C: 24 - 790 (UniProt: Q09161)

PDB	External Database	Details
Met 23	-	initiating methionine
Val 479	Ala 479	conflict
Ala 791	-	expression tag
Glu 792	-	expression tag
Asn 793	-	expression tag
Leu 794	-	expression tag
Tyr 795	-	expression tag
Phe 796	-	expression tag
Gln 797	-	expression tag
Gly 798	-	expression tag
His 799	-	expression tag
His 800	-	expression tag
His 801	-	expression tag
His 802	-	expression tag
His 803	-	expression tag
His 804	-	expression tag

A: 1 - 156 (UniProt: P52298)

PDB	External Database	Details
Gly -19	-	expression tag
Pro -18	-	expression tag
Leu -17	-	expression tag
His -16	-	expression tag
Met -15	-	expression tag
Gly -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
Pro -11	-	expression tag
Glu -10	-	expression tag
Phe -9	-	expression tag
Pro -8	-	expression tag
Gly -7	-	expression tag
Arg -6	-	expression tag
Leu -5	-	expression tag
Glu -4	-	expression tag
Ala -3	-	expression tag
Ala -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag

B: -9 - 20 (UniProt: Q86YN6)

PDB	External Database	Details
Ace -10	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	114643.4
Non-Polymers*	Number of molecules	2
	Total formula weight	811.7
All*	Total formula weight	115455.1

*Water molecules are not included.