6CRN
Structure of the USP15 deubiquitinase domain in complex with a high-affinity first-generation Ubv
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ubiquitin carboxyl-terminal hydrolase 15 | polymer | 360 | 40959.3 | 4 | UniProt (Q9Y4E8) Pfam (PF00443) | Homo sapiens (Human) | Deubiquitinating enzyme 15,Ubiquitin thioesterase 15,Ubiquitin-specific-processing protease 15,Unph-2,Unph4 |
| 2 | E, F, G, H (E, F, G, H) | Ubiquitin variant 15.2 | polymer | 81 | 9074.4 | 4 | Homo sapiens | Ubv 15.2 | |
| 3 | I, J, K, L (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 275 - 470 (UniProt: Q9Y4E8)
A, B, C, D: 471 - 624 (UniProt: Q9Y4E8)
| PDB | External Database | Details |
|---|---|---|
| Ser 270 | - | expression tag |
| Gly 271 | - | expression tag |
| Ala 272 | - | expression tag |
| Ala 273 | - | expression tag |
| Ala 274 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 625 | - | expression tag |
| Ser 626 | - | expression tag |
| Gly 627 | - | expression tag |
| Glx 628 | - | expression tag |
| Asn 629 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 200134.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 200396.5 |
