6CLV
Staphylococcus aureus Dihydropteroate Synthase (saDHPS) F17L E208K double mutant structure
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Dihydropteroate synthase | polymer | 291 | 32406.9 | 4 | UniProt (O05701) Pfam (PF00809) In PDB | Staphylococcus aureus | DHPS,Dihydropteroate pyrophosphorylase |
2 | A, B, C | 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide | non-polymer | 442.5 | 3 | Chemie (6MB) | |||
3 | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 267 (UniProt: O05701)
PDB | External Database | Details |
---|---|---|
Met -23 | - | initiating methionine |
Gly -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
Ser -11 | - | expression tag |
Ser -10 | - | expression tag |
Gly -9 | - | expression tag |
His -8 | - | expression tag |
Ile -7 | - | expression tag |
Glu -6 | - | expression tag |
Gly -5 | - | expression tag |
Arg -4 | - | expression tag |
His -3 | - | expression tag |
Met -2 | - | expression tag |
Leu -1 | - | expression tag |
Glu 0 | - | expression tag |
Leu 17 | Phe 17 | engineered mutation |
Lys 208 | Glu 208 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 129627.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1327.4 | |
All* | Total formula weight | 130955.1 |