6CIK
Pre-Reaction Complex, RAG1(E962Q)/2-intact/nicked 12/23RSS complex in Mn2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | V(D)J recombination-activating protein 1 | polymer | 625 | 71716.1 | 2 | UniProt (P15919) Pfam (PF12940) | Mus musculus (Mouse) | RAG-1 |
| 2 | B, D (B, D) | V(D)J recombination-activating protein 2 | polymer | 359 | 40036.5 | 2 | UniProt (P21784) Pfam (PF03089) | Mus musculus (Mouse) | RAG-2 |
| 3 | E (N) | High mobility group protein B1 | polymer | 163 | 18897.9 | 1 | UniProt (P09429) Pfam (PF09011) Pfam (PF00505) | Homo sapiens (Human) | High mobility group protein 1,HMG-1 |
| 4 | F (F) | Intact 12RSS substrate reverse strand | polymer | 39 | 12140.8 | 1 | Homo sapiens | ||
| 5 | G (I) | Intact 12RSS substrate forward strand | polymer | 40 | 12194.9 | 1 | Homo sapiens | ||
| 6 | H (G) | Nicked 23RSS intermediate reverse strand | polymer | 55 | 16978.9 | 1 | Homo sapiens | ||
| 7 | I (J) | DNA (5'-D(*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3') | polymer | 15 | 4551.0 | 1 | Homo sapiens | ||
| 8 | J (M) | Nicked 23RSS intermediate forward strand | polymer | 40 | 12326.0 | 1 | Homo sapiens | ||
| 9 | K, M (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 10 | L, N (A, C) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 11 | O, P, Q, R, S (A, B, C, D, G) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, C: 384 - 1008 (UniProt: P15919)
| PDB | External Database | Details |
|---|---|---|
| Gln 962 | Glu 962 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 300594.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 240.7 | |
| All* | Total formula weight | 300835.3 |
