6CDU

Crystal structure of a chimeric human alpha1GABAA receptor in complex with alphaxalone

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	chimeric alpha1GABAA receptor	polymer	324	37225.4	10	UniProt (E0SJQ4) UniProt (P14867) Pfam (PF02931) Pfam (PF02932) In PDB	Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))	GABA(A) receptor subunit alpha-1,GABA(A) receptor subunit alpha-1
2	A, B, D, E, F...	(3a,5a)-3-Hydroxypregnane-11,20-dione	non-polymer		332.5	10	Chemie (EY4)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 1 - 199 (UniProt: E0SJQ4)
A, B, C, D, E, F, G, H, I, J: 222 - 313 (UniProt: P14867)
A, B, C, D, E, F, G, H, I, J: 388 - 417 (UniProt: P14867)

PDB	External Database	Details
Gly 314	-	linker
Val 315	-	linker
Glu 316	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	372253.6
Non-Polymers*	Number of molecules	10
	Total formula weight	3324.8
All*	Total formula weight	375578.4

*Water molecules are not included.