6CCX
NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Apolipoprotein A-I | polymer | 200 | 23234.3 | 2 | UniProt (P02647) Pfam (PF01442) In PDB | Homo sapiens (Human) | ApoA-I,Apolipoprotein A1 |
| 2 | B | GTPase KRas | polymer | 187 | 21302.3 | 1 | UniProt (P01116) Pfam (PF00071) In PDB | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 3 | B, C, A | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 64 | Chemie (PCW) | |||
| 4 | C, B, A | O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine | non-polymer | 788.0 | 16 | Chemie (17F) | |||
| 5 | B | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 6 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | B | (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium | non-polymer | 447.8 | 1 | Chemie (EWS) |
Sequence modifications
A, C: 201 - 398 (UniProt: P02647)
B: 1 - 185 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly 199 | - | expression tag |
| Pro 200 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67770.9 | |
| Non-Polymers* | Number of molecules | 83 |
| Total formula weight | 63978.7 | |
| All* | Total formula weight | 131749.6 |
