6C79
Conformational Changes in a Class A Beta lactamase that Prime it for Catalysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase Toho-1 | polymer | 261 | 28045.7 | 1 | UniProt (Q47066) | Escherichia coli | |
| 2 | B (A) | (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid | non-polymer | 455.5 | 1 | Chemie (CE3) PubChem (2632) PubChem (44555) PubChem (456256) PubChem (5361298) PubChem (5361354) PubChem (5479527) PubChem (5916965) PubChem (6540461) PubChem (6604086) PubChem (6914272) PubChem (7566336) PubChem (9703676) PubChem (9868614) PubChem (12763159) PubChem (12971804) PubChem (16396922) PubChem (53850837) PubChem (5742673) PubChem (53850835) PubChem (53850836) PubChem (6398645) PubChem (12763160) PubChem (87963272) PubChem (88595673) PubChem (88595674) PubChem (123797533) PubChem (131711503) | |||
| 3 | C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G (A) | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence modifications
A: 29 - 288 (UniProt: Q47066)
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | - | expression tag |
| Ala 70 | Ser 73 | conflict |
| Asn 272 | Arg 275 | conflict |
| Asn 274 | Arg 277 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28045.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 839.7 | |
| All* | Total formula weight | 28885.4 |
