6C79
Conformational Changes in a Class A Beta lactamase that Prime it for Catalysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-lactamase Toho-1 | polymer | 261 | 28045.7 | 1 | UniProt (Q47066) Pfam (PF00144) Pfam (PF00905) Pfam (PF13354) In PDB | Escherichia coli | |
| 2 | A | (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid | non-polymer | 455.5 | 1 | Chemie (CE3) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence modifications
A: 29 - 288 (UniProt: Q47066)
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | - | expression tag |
| Ala 70 | Ser 73 | conflict |
| Asn 272 | Arg 275 | conflict |
| Asn 274 | Arg 277 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28045.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 839.7 | |
| All* | Total formula weight | 28885.4 |
