6C5C
Crystal structure of the 3-dehydroquinate synthase (DHQS) domain of Aro1 from Candida albicans SC5314 in complex with NADH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-dehydroquinate synthase | polymer | 390 | 42784.6 | 2 | UniProt (Q5AME2) Pfam (PF01761) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | Aro1p |
| 2 | C, N (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, E, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 13 | Chemie (EDO) | |||
| 4 | M (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | S, T (A, B) | water | water | 18.0 | 389 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 387 (UniProt: Q5AME2)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85569.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2169.2 | |
| All* | Total formula weight | 87738.5 |
