Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003856 | molecular_function | 3-dehydroquinate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016838 | molecular_function | carbon-oxygen lyase activity, acting on phosphates |
| B | 0003856 | molecular_function | 3-dehydroquinate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0016838 | molecular_function | carbon-oxygen lyase activity, acting on phosphates |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | ASP42 |
| A | ASP116 |
| A | THR136 |
| A | THR137 |
| A | ASP143 |
| A | SER144 |
| A | LYS149 |
| A | ASN159 |
| A | PHE176 |
| A | THR179 |
| A | LEU180 |
| A | ASN44 |
| A | EDO409 |
| A | HOH522 |
| A | HOH523 |
| A | HOH540 |
| A | HOH544 |
| A | HOH571 |
| A | HOH577 |
| A | HOH579 |
| A | HOH585 |
| A | HOH600 |
| A | MET45 |
| A | HOH605 |
| A | PRO78 |
| A | GLU80 |
| A | LYS83 |
| A | GLY111 |
| A | GLY112 |
| A | VAL113 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | THR43 |
| A | CYS75 |
| A | HOH556 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | TYR51 |
| A | THR73 |
| A | TYR74 |
| A | CYS75 |
| A | HOH520 |
| A | HOH618 |
| A | HOH639 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 404 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | ILE8 |
| A | GLY147 |
| A | GLN166 |
| A | PRO167 |
| A | VAL170 |
| A | HOH529 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | ARG85 |
| A | PRO155 |
| A | HOH581 |
| A | HOH625 |
| B | HOH513 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | ALA305 |
| A | ARG308 |
| A | LYS365 |
| A | ILE366 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | PRO303 |
| A | VAL304 |
| A | HOH614 |
| B | PRO302 |
| B | LYS365 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | ASP143 |
| A | LYS194 |
| A | LEU260 |
| A | NAD401 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | GLU208 |
| A | LYS311 |
| A | CYS312 |
| A | HOH507 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 411 |
| Chain | Residue |
| A | LYS88 |
| A | HOH710 |
| B | LYS88 |
| B | HOH664 |
| site_id | AD3 |
| Number of Residues | 28 |
| Details | binding site for residue NAD B 401 |
| Chain | Residue |
| B | HOH562 |
| B | HOH580 |
| B | HOH587 |
| B | ASP42 |
| B | ASN44 |
| B | MET45 |
| B | PRO78 |
| B | GLU80 |
| B | LYS83 |
| B | GLY111 |
| B | GLY112 |
| B | VAL113 |
| B | ASP116 |
| B | THR136 |
| B | THR137 |
| B | ASP143 |
| B | SER144 |
| B | LYS149 |
| B | ASN159 |
| B | PHE176 |
| B | THR179 |
| B | LEU180 |
| B | EDO404 |
| B | HOH502 |
| B | HOH503 |
| B | HOH517 |
| B | HOH535 |
| B | HOH553 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | LEU96 |
| B | GLY99 |
| B | CYS100 |
| B | MET126 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| B | ILE8 |
| B | GLY147 |
| B | GLN166 |
| B | PRO167 |
| B | VAL170 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | ASP143 |
| B | LYS194 |
| B | LEU260 |
| B | NAD401 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | ILE270 |
| B | ILE286 |
| B | LYS290 |
| B | SER321 |
| B | ILE322 |
| B | LEU386 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor; for 3-dehydroquinate synthase activity","evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 59 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]} |
