6BWY

DNA substrate selection by APOBEC3G

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	I, C, D, F	DNA (30-MER)	polymer	30	9357.1	4		synthetic construct
2	A, B, E, G	Protection of telomeres protein 1, DNA dC->dU-editing enzyme APOBEC-3G fusion	polymer	361	41966.4	4	UniProt (O13988) UniProt (Q9HC16) Pfam (PF02765) Pfam (PF05240) In PDB	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	APOBEC-related cytidine deaminase,ARCD,APOBEC-related protein 9,ARP-9,CEM-15,CEM15,Deoxycytidine deaminase,A3G
3	G, I, C, D, F...	PHOSPHATE ION	non-polymer		95.0	15	Chemie (PO4)
4	A, B, E, G	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5		water	water		18.0	57	Chemie (HOH)

Sequence modifications

A, B, E, G: 25 - 194 (UniProt: O13988)

PDB	External Database	Details
Met 24	-	initiating methionine

A, B, E, G: 195 - 384 (UniProt: Q9HC16)

PDB	External Database	Details
Lys 234	Leu 234	engineered mutation
Ala 243	Cys 243	engineered mutation
Lys 310	Phe 310	engineered mutation
Ala 321	Cys 321	engineered mutation
Ala 356	Cys 356	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	205293.8
Non-Polymers*	Number of molecules	19
	Total formula weight	1686.2
All*	Total formula weight	206980.0

*Water molecules are not included.