6BWY
DNA substrate selection by APOBEC3G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (I, C, D, F) | DNA (30-MER) | polymer | 30 | 9357.1 | 4 | synthetic construct | ||
| 2 | E, F, G, H (A, B, E, G) | Protection of telomeres protein 1, DNA dC->dU-editing enzyme APOBEC-3G fusion | polymer | 361 | 41966.4 | 4 | UniProt (O13988) UniProt (Q9HC16) Pfam (PF02765) Pfam (PF05240) | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | APOBEC-related cytidine deaminase,ARCD,APOBEC-related protein 9,ARP-9,CEM-15,CEM15,Deoxycytidine deaminase,A3G |
| 3 | AA, I, J, K, L... (G, I, C, D, F...) | PHOSPHATE ION | non-polymer | 95.0 | 15 | Chemie (PO4) | |||
| 4 | M, Q, T, X (A, B, E, G) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | BA, CA, DA, EA, FA... (I, C, D, A, B...) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A, B, E, G: 25 - 194 (UniProt: O13988)
A, B, E, G: 195 - 384 (UniProt: Q9HC16)
| PDB | External Database | Details |
|---|---|---|
| Met 24 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Lys 234 | Leu 234 | engineered mutation |
| Ala 243 | Cys 243 | engineered mutation |
| Lys 310 | Phe 310 | engineered mutation |
| Ala 321 | Cys 321 | engineered mutation |
| Ala 356 | Cys 356 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 205293.8 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1686.2 | |
| All* | Total formula weight | 206980.0 |
