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6BT0

CRYSTAL STRUCTURE OF RHEB IN COMPLEX WITH COMPOUND NR1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
GTP-binding protein Rhebpolymer17820236.04UniProt (Q15382)
Pfam (PF00071)
Homo sapiens (Human)Ras homolog enriched in brain
2E, G, J, L
(A, B, C, D)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
3F, H, K, M
(A, B, C, D)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.24Chemie (GDP)
4I
(B)
4-bromo-6-[(3,4-dichlorophenyl)sulfanyl]-1-{[4-(dimethylcarbamoyl)phenyl]methyl}-1H-indole-2-carboxylic acidnon-polymer578.31Chemie (E7V)
5N, O, P, Q
(A, B, C, D)
waterwater18.018Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 169 (UniProt: Q15382)
PDBExternal DatabaseDetails
Ser 0-expression tag
Leu 170-expression tag
Glu 171-expression tag
His 172-expression tag
His 173-expression tag
His 174-expression tag
His 175-expression tag
His 176-expression tag
His 177-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight80944.2
Non-Polymers*Number of molecules9
Total formula weight2448.3
All*Total formula weight83392.5
*Water molecules are not included.

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PDB entries from 2025-07-02

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