6BQ8
Joint X-ray/neutron structure of PKG II CNB-B domain in complex with 8-pCPT-cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cGMP-dependent protein kinase 2 | polymer | 152 | 17394.4 | 1 | UniProt (Q13237) Pfam (PF00027) In PDB | Homo sapiens (Human) | cGK2,cGMP-dependent protein kinase II,cGKII |
| 2 | A | 2-(~2~H_2_)amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2-hydroxy-7-(~2~H)hydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl](~2~H)-1,9-dihydro-6H-purin-6-one | non-polymer | 487.8 | 1 | Chemie (WNU) | |||
| 3 | A | STRONTIUM ION | non-polymer | 87.6 | 1 | Chemie (SR) | |||
| 4 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | water | water | 18.0 | 40 | Chemie (DOD) |
Sequence modifications
A: 269 - 418 (UniProt: Q13237)
| PDB | External Database | Details |
|---|---|---|
| Gly 267 | - | expression tag |
| Ser 268 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17394.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 693.6 | |
| All* | Total formula weight | 18088.0 |
