6BC0
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rho guanine nucleotide exchange factor 28 | polymer | 150 | 17533.2 | 1 | UniProt (Q8N1W1) Pfam (PF17838) | Homo sapiens (Human) | 190 kDa guanine nucleotide exchange factor,p190RhoGEF,Rho guanine nucleotide exchange factor |
| 2 | B (F) | Transforming protein RhoA | polymer | 185 | 20865.9 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (Human) | Rho cDNA clone 12,h12 |
| 3 | C (F) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (F) | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
| 5 | E, F (A, F) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 1049 - 1194 (UniProt: Q8N1W1)
F: 1 - 181 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Gly 1045 | - | expression tag |
| Ile 1046 | - | expression tag |
| Leu 1047 | - | expression tag |
| Asp 1048 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ile -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Asp 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38399.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 563.6 | |
| All* | Total formula weight | 38962.6 |
