6BC0
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Rho guanine nucleotide exchange factor 28 | polymer | 150 | 17533.2 | 1 | UniProt (Q8N1W1) Pfam (PF17838) In PDB | Homo sapiens (Human) | 190 kDa guanine nucleotide exchange factor,p190RhoGEF,Rho guanine nucleotide exchange factor |
2 | F | Transforming protein RhoA | polymer | 185 | 20865.9 | 1 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (Human) | Rho cDNA clone 12,h12 |
3 | F | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | F | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
5 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 1049 - 1194 (UniProt: Q8N1W1)
F: 1 - 181 (UniProt: P61586)
PDB | External Database | Details |
---|---|---|
Gly 1045 | - | expression tag |
Ile 1046 | - | expression tag |
Leu 1047 | - | expression tag |
Asp 1048 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ile -2 | - | expression tag |
Leu -1 | - | expression tag |
Asp 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 38399.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 563.6 | |
All* | Total formula weight | 38962.6 |