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6BBH

The CRAC channel Orai in an unlatched-closed conformation; K163W loss-of-function mutation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Calcium release-activated calcium channel protein 1polymer21424284.324UniProt (Q9U6B8)
Pfam (PF07856)
In PDB
Drosophila melanogaster (Fruit fly)Protein orai,dOrai
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X: 133 - 341 (UniProt: Q9U6B8)
PDBExternal DatabaseDetails
Trp 163Lys 163engineered mutation
Ser 224Cys 224engineered mutation
Thr 283Cys 283engineered mutation
Glu 342-expression tag
Gly 343-expression tag
Glu 344-expression tag
Glu 345-expression tag
Phe 346-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains24
Total formula weight582822.4
All*Total formula weight582822.4
*Water molecules are not included.

222415

PDB entries from 2024-07-10

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