6B9X

Crystal structure of Ragulator

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ragulator complex protein LAMTOR1	polymer	161	17762.8	1	UniProt (Q6IAA8) Pfam (PF15454)	Homo sapiens (Human)	Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1,Lipid raft adaptor protein p18,Protein associated with DRMs and endosomes,p27Kip1-releasing factor from RhoA,p27RF-Rho
2	B (B)	Ragulator complex protein LAMTOR2	polymer	126	13588.5	1	UniProt (Q9Y2Q5) Pfam (PF03259)	Homo sapiens (Human)	Endosomal adaptor protein p14,Late endosomal/lysosomal Mp1-interacting protein,Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2,Mitogen-activated protein-binding protein-interacting protein,MAPBP-interacting protein,Roadblock domain-containing protein 3
3	C (C)	Ragulator complex protein LAMTOR3	polymer	124	13637.7	1	UniProt (Q9UHA4) Pfam (PF08923)	Homo sapiens (Human)	Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3,MEK-binding partner 1,Mp1,Mitogen-activated protein kinase kinase 1-interacting protein 1,Mitogen-activated protein kinase scaffold protein 1
4	D (D)	Ragulator complex protein LAMTOR4	polymer	99	10753.2	1	UniProt (Q0VGL1)	Homo sapiens (Human)	Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4
5	E (E)	Hepatitis B virus x interacting protein	polymer	173	18178.5	1	UniProt (A0A0C4DGV4) Pfam (PF16672) UniProt (by SIFTS) (O43504)	Homo sapiens (Human)	Ragulator complex protein LAMTOR5
6	F, G, H, I, J (A, B, C, D, E)	water	water		18.0	290	Chemie (HOH)

Sequence modifications

B: 1 - 125 (UniProt: Q9Y2Q5)

PDB	External Database	Details
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	73920.7
All*	Total formula weight	73920.7

*Water molecules are not included.